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  1. 12/07/2011 Quels effets d’une déshydratation sur les fonctions cognitives et le bien être ?

    Pross N.

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  2. 12/07/2011 Influence de 24h Restriction de Fluides sur L’humeur et marqueurs physiologiques de l’hydratation chez la femme.

    Pross N, Barnouin R, Girard N, Santoro F, Klein A, Guelinckx I, Demazières A, Le Bellego L.

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  3. 11/24/2011 Comparaison des effets d'une restriction de sommeil chez des volontaires sains et des patients insomniaques adultes : polysomnographie, actigraphie et holter cardiaque

    Cornette F, Lerner C, Viardot G, Muzet A, Staner L

    OBJECTIFS : Le but de cette étude consiste à comparer des volontaires sains (VS) et des patients insomniaques (PI) au cours d’une restriction de sommeil (RS), au niveau du sommeil (PSG), de l’activité motrice (actigraphie) et de l’activité cardiaque autonome (holter). Read more >
  4. 11/24/2011 Comparaison de la variabilité intra- et inter- individuelle des paramètres polysomnographiques, chez des volontaires sains et des patients insomniaques adultes

    Cornette F, Lerner C, Metzger D, Pross N, Muzet A, Staner L

    OBJECTIFS: Cette étude évalue la variabilité inter- (VAR ir) et intra- (VAR ia) sujets de paramètres sommeil chez des volontaires sains (VS) comparés à des patients insomniaques (PI).
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  5. 11/15/2011 Influence of an acute fluid restriction on mood and cognition in women in daily life.

    Pross N.

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  6. 11/12/2011 The novel compound BNC210 partially reduces Panic Symptom Scale scores in a model of CCK-4 induced panic in healthy volunteers.

    O'Connor S, Doolin E, Pross N, Metzger D, Guichard N, Andriambeloson E, Kremmidiotis G, Danjou P.

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  7. 11/02/2011 Oculomotricity does not influence resting gamma eeg activity following a subanesthetic dose of ketamine

    Boeijinga P, DanjouP, Otmani S, Monnier A, MetzgerD and Patroneva A

    Ketamine a NMDA non-competitive antagonist has been used as a model of psychosis for many years; more recently some preliminary clinical data have suggested a rapid and long lasting antidepressant effect of a single dose of ketamine. In rodents, ketamine has been shown to increase gamma frequency EEG power and produce nystagmus...

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  8. 10/26/2011 Influence of a 24h Fluid Restriction on Mood and Physiological Markers of Dehydration in Women.

    Pross N, Chevillotte E, Barnouin R, Girard N, Santoro F, Klein A, Demazières A, Le Bellego L.

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  9. 10/03/2011 ERP decomposition techniques to infer functional modules in the human brain: a neurotechnology lesson from cognitive responses and vigilance studies

    Boeijinga P., Viardot G., Pross N.

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  10. 09/13/2011 Use of an adaptative design to adjust for an unknown response rate by sample size readjustment: case of a CCK-induced anxiety model as a POC study.

    Danjou P, Pross N, Metzger D, Kremmidiotis G, Doolin L, Wagner S, Vandehende F, O’Connor S.

    -Existing POC designs in anxiety disorders.
    -Preclinical data on BNC210 and model alignment between species.
    -Principle of model and historical data for response rate and magnitude of drug response
    -Simulations and hypotheses for sample size based on in-house data and literature

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