Pross N.
Read more >Pross N, Barnouin R, Girard N, Santoro F, Klein A, Guelinckx I, Demazières A, Le Bellego L.
Read more >Cornette F, Lerner C, Viardot G, Muzet A, Staner L
OBJECTIFS : Le but de cette étude consiste à comparer des volontaires sains (VS) et des patients insomniaques (PI) au cours d’une restriction de sommeil (RS), au niveau du sommeil (PSG), de l’activité motrice (actigraphie) et de l’activité cardiaque autonome (holter). Read more >Cornette F, Lerner C, Metzger D, Pross N, Muzet A, Staner L
OBJECTIFS: Cette étude évalue la variabilité inter- (VAR ir) et intra- (VAR ia) sujets de paramètres sommeil chez des volontaires sains (VS) comparés à des patients insomniaques (PI).Pross N.
Read more >O'Connor S, Doolin E, Pross N, Metzger D, Guichard N, Andriambeloson E, Kremmidiotis G, Danjou P.
Read more >Boeijinga P, DanjouP, Otmani S, Monnier A, MetzgerD and Patroneva A
Ketamine a NMDA non-competitive antagonist has been used as a model of psychosis for many years; more recently some preliminary clinical data have suggested a rapid and long lasting antidepressant effect of a single dose of ketamine. In rodents, ketamine has been shown to increase gamma frequency EEG power and produce nystagmus...
Read more >Pross N, Chevillotte E, Barnouin R, Girard N, Santoro F, Klein A, Demazières A, Le Bellego L.
Read more >Boeijinga P., Viardot G., Pross N.
Read more >Danjou P, Pross N, Metzger D, Kremmidiotis G, Doolin L, Wagner S, Vandehende F, O’Connor S.
-Existing POC designs in anxiety
disorders.
-Preclinical data on BNC210 and model
alignment between species.
-Principle of model and historical data
for response rate and magnitude of drug response
-Simulations and hypotheses for sample
size based on in-house data and literature