Magnetic Resonance Imaging (MRI) allows to explore in detail numerous organs such as brain, spine, joints and soft tissues. The quality of images obtained is by far superior to the one obtained with conventional X-rays and is more precise than scans. In addition to anatomical images, MRI can be used to generate metabolism information through what is called localised spectroscopy or Magnetic Resonance Spectroscopy (MRS). MRS is the only non invasive technique able to measure chemicals directly within the body.
Since the 1990s, technical improvements have led to functional Magnetic Resonance Imaging (fMRI), which has allowed a tremendous boom in the undertanding of brain functioning. This technique is based on changes in signal intensity in images of the humain brain during task-specific brain stimulation and is called Blood Oxygenation Level Dependent (BOLD) contrast imaging.
Such techniques are now being used to investigate effects of central nervous system active drug on the brain. The use of pharmacological MRI (phMRI) is a promising tool in the pharmacological development.
